| Title |
Isotretinoin, depression and suicide: a review of the evidence.
|
|---|---|
| Published in |
British Journal of General Practice, February 2005
|
| Pubmed ID | |
| Authors |
Parker Magin, Dimity Pond, Wayne Smith |
| Abstract |
There is currently considerable controversy regarding a proposed causal relationship between the use of isotretinoin and depression and suicide. A search was made of the MEDLINE, EMBASE and PsychINFO databases using the search terms 'isotretinoin', 'depression' and 'suicide'. Despite numerous case reports linking isotretinoin to depression, suicidal ideation and suicide, there is, as yet, no clear proof of an association. While isotretinoin, used to treat acne vulgaris, has not been demonstrated to be associated with depression or suicide, the possibility of a relatively rare idiosyncratic adverse effect remains. GPs have a role in the clinical application of these findings. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 22% |
| Colombia | 2 | 11% |
| United Kingdom | 1 | 6% |
| Australia | 1 | 6% |
| Unknown | 10 | 56% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 89% |
| Practitioners (doctors, other healthcare professionals) | 2 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 2 | 2% |
| Australia | 2 | 2% |
| Czechia | 1 | <1% |
| Unknown | 100 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 29 | 28% |
| Student > Master | 12 | 11% |
| Researcher | 9 | 9% |
| Student > Ph. D. Student | 8 | 8% |
| Student > Postgraduate | 5 | 5% |
| Other | 16 | 15% |
| Unknown | 26 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 45 | 43% |
| Agricultural and Biological Sciences | 6 | 6% |
| Psychology | 6 | 6% |
| Nursing and Health Professions | 3 | 3% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Other | 15 | 14% |
| Unknown | 27 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 131. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2024.
All research outputs
#324,235
of 25,743,152 outputs
Outputs from British Journal of General Practice
#118
of 4,932 outputs
Outputs of similar age
#492
of 159,553 outputs
Outputs of similar age from British Journal of General Practice
#1
of 16 outputs
Altmetric has tracked 25,743,152 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,932 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.7. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 159,553 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.