Comparison of Centor and McIsaac scores in primary care: a meta-analysis over multiple thresholds

@SarahDRasmussen @krishnakolidoc This provides estimates of the probability of Strep throat based on symptoms & signs. That’s the basis of my comments on likelihood of Strep. https://t.co/DS1jTuE0cf

@jason_om @JennaPrice Even the highest Centor score only means a 50:50 chance it is a bacterial infection. https://t.co/DS1jTuE0cf

@KateCushing2 @DrSdeG Yes. This is my go-to reference as it considers test characteristics in relation to background prevalence. (Also it is by folk in my own department) https://t.co/BE57ynjAAu

@Azeem_Majeed Symptom scoring systems pretty good at ruling out Streptococcal sore throat, but even with a high score only about 50% have Streptococcal sore throat https://t.co/BE57ynjAAu

@DrGoblin3 Bear in mind that even a high symptom score has a PPV of only around 1 in 2 for bacterial infection. https://t.co/6FTOcpHOAR

@DrSdeG @goodallsix How do you know it’s a bacterial infection? Rapid antigen test? Centor scores (ie: clinical signs) have low PPV https://t.co/DS1jTuE0cf

@RichardLehman1 @sfinnikin @mgtmccartney @janewilcock @TomPMarshall @susan_bewley @DrSimonHodes @JMichaelMcW @alf_collins @DrAoifeMolloy @drtimwilson @AntibioticResis @AntibioticDoc @TheUrgentNeed @MartinRCGP @rcgp @trishgreenhalgh @NICEComms @PaulGlasziou

RT @BJGPjournal: Meta-analysis compares Centor and McIsaac scores in primary care for the diagnosis of group A beta-haemolytic streptococcu…

Meta-analysis compares Centor and McIsaac scores in primary care for the diagnosis of group A beta-haemolytic streptococcus infection https://t.co/mfIOQ5YdNM